CAS 1801896-05-8
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2 produits concernés.
EBI-1051
CAS :EBI-1051 is a highly potent and orally efficacious inhibitor of MEK (IC50: 3.9 nM).Formule :C18H15F2IN2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.22N-((1,3-Dihydroxypropan-2-yl)oxy)-7-fluoro-6-((2-fluoro-4-iodophenyl)amino)benzofuran-5-carboxamide
CAS :<p>N-((1,3-Dihydroxypropan-2-yl)oxy)-7-fluoro-6-(2-fluoro-4-iodophenyl)amino)benzofuran-5 -carboxamide (BX795) is a potent and selective inhibitor of the immune checkpoint protein PD1, which is expressed on T cells. This drug binds to the extracellular domain of PD1 and blocks its interaction with the ligands PDL1 and PDL2. BX795 inhibits the activation of T cells by blocking the signal transduction pathway induced by PD1 binding to its ligands. This drug has been shown to have an excellent safety profile in preclinical studies and will be tested in clinical trials for cancer immunotherapy.</p>Formule :C18H15F2IN2O5Degré de pureté :Min. 95%Masse moléculaire :504.2 g/mol
