
CAS 1863916-88-4
:Dolutegravir Impurity 4
CAS :Formule :C20H20FN3O5Couleur et forme :White To Off-White SolidMasse moléculaire :401.39Defluoro Dolutegravir (>85%)
CAS :Applications Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);Formule :C20H20FN3O5Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :401.39Defluoro dolutegravir
CAS :Please enquire for more information about Defluoro dolutegravir including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C20H20FN3O5Degré de pureté :Min. 95%Masse moléculaire :401.4 g/mol



