CAS 1873373-33-1

Trk-in-3

CAS : 1873373-33-1

Trk-in-3 is an inhibitor specifically targeting tyrosine kinase receptors, derived from a combination of synthesized natural compounds. This inhibitor functions by selectively binding to the ATP-binding site of Trk receptors, thus disrupting downstream signaling pathways that are crucial for cellular proliferation and survival.

Formule : C₂₀H₁₉F₅N₄O₄

Degré de pureté : Min. 95%

Masse moléculaire : 474.4 g/mol

Ref: 3D-YZC37333

PF-06733804

CAS : 1873373-33-1

PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, and 2.2 nM for TrkA, TrkB, and TrkC) with anti-hyperalgesic effect.

Formule : C₂₀H₁₉F₅N₄O₄

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 474.38

Ref: TM-T13207