CAS 1997338-61-0

Canagliflozin-d4

CAS : 1997338-61-0

Formule : C₂₄H₂₁D₄FO₅S

Couleur et forme : White To Off-White Solid

Masse moléculaire : 448.54

Ref: 4Z-C-152001

Canagliflozin D4

Produit contrôlé

CAS : 1997338-61-0

Canagliflozin D4 is a synthetic compound that inhibits the SGLT2 transporter and increases the renal excretion of glucose. Canagliflozin D4 is used in the treatment of type 2 diabetes mellitus and is marketed as Invokana. Canagliflozin D4 is a racemic mixture of two enantiomers, with (S)-canagliflozin being more potent than (R)-canagliflozin. The reaction monitoring technique was used to monitor the production of metformin from canagliflozin D4 by extraction with diethyl ether. A validated method for quantification and monitoring was developed using deuterated water for flow rate linearity optimization. This method was applied to plasma samples obtained from healthy Indian subjects who were administered canagliflozin D4 at variable doses over 24 hours. The pharmacokinetic parameters were determined for each subject, resulting in an optimization of this drug dose range.

Formule : C₂₄H₂₁D₄FO₅S

Degré de pureté : Min. 95%

Masse moléculaire : 448.54 g/mol

Ref: 3D-FC146109

Canagliflozin-d4

CAS : 1997338-61-0

Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.

Formule : C₂₄H₂₅FO₅S

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 448.54

Ref: TM-T10669