CAS 2002-44-0
:L-Prolyl-L-leucylglycinamide
Description :
L-Prolyl-L-leucylglycinamide, avec le numéro CAS 2002-44-0, est un peptide synthétique composé de trois acides aminés : proline, leucine et glycine. Ce composé se caractérise par sa séquence spécifique, qui influence son activité biologique et ses interactions. Les peptides comme L-Prolyl-L-leucylglycinamide sont souvent étudiés pour leurs rôles potentiels dans divers processus physiologiques, y compris leurs effets sur la neurotransmission et la régulation hormonale. La présence de proline dans sa structure peut contribuer à des propriétés conformationnelles uniques, affectant potentiellement sa stabilité et sa solubilité. De plus, la nature hydrophobe de la leucine peut influencer ses interactions avec les membranes biologiques ou les protéines. L-Prolyl-L-leucylglycinamide peut également présenter des affinités de liaison spécifiques aux récepteurs, ce qui le rend intéressant pour la recherche pharmacologique. Dans l'ensemble, les caractéristiques de ce composé, y compris sa composition en acides aminés et sa séquence, jouent un rôle crucial dans la détermination de sa fonctionnalité et de ses applications potentielles en biochimie et en chimie médicinale.
Formule :C13H24N4O3
InChI :InChI=1/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1
Code InChI :InChIKey=NOOJLZTTWSNHOX-UWVGGRQHSA-N
SMILES :[C@@H](NC(=O)[C@@H]1CCCN1)(C(NCC(N)=O)=O)CC(C)C
Synonymes :- 2-Pyrrolidinecarboxamide, N-[1-[(carbamoylmethyl)carbamoyl]-3-methylbutyl]-
- 26: PN: US6093797 PAGE: 15 claimed protein
- 27: PN: US6093797 PAGE: 15 claimed protein
- 2: PN: WO2009039992 PAGE: 107 claimed protein
- 7-9-Oxytocin
- <span class="text-smallcaps">L</smallcap>-Proline-<smallcap>L</span>-leucine-glycine-amide
- <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-leucyl-glycine amide
- <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-leucylglycinamide
- <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-leucylglycylamide
- Glycinamide, <span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</span>-leucyl-
- H-Pro-Leu-Gly-NH2
- H-Pro-Leu-Gly-NH<sub>2</sub>
- L-Prolyl-L-leucylglycinamide, hemihydrate
- L-prolyl-L-leucylglycinamide
- MSH-release inhibiting factor I
- Melanocyte-Stimulating Hormone-Release Inhibiting Factor
- Melanocyte-stimulating hormone release-inhibiting factor 1
- Melanocyte-stimulating hormone release-inhibiting factor I
- Melanocyte-stimulating hormone release-inhibiting factor I (ox)
- Melanostatin I (ox)
- Mif-1
- Mif-I
- Oxytocin C-terminal tripeptide
- Pro-Leu-Gly-NH<sub>2</sub>
- Prolyleucyl-glycinamide
- Prolylleucylglycine amide
- Pro-Leu-Gly-NH2
- Glycinamide, L-prolyl-L-leucyl-
- L-Proline-L-leucine-glycine-amide
- Melanocyte-stimulati
- (2S)-N-[(1S)-1-[(2-amino-2-keto-ethyl)carbamoyl]-3-methyl-butyl]pyrrolidine-2-carboxamide
- Melanostatin, MIF-I, Oxytocin fragment 7-9
- MIF, AMIDE
- MELANOCYTE STIMULATING HORMONE RELEASE INHIBITING FACTOR, AMIDE
- (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
- MSH RELEASE INHIBITING FACTOR, AMIDE
- MELANOCYTE STIMULATING HORMONE RELEASING FACTOR
- PLG-NH2
- (2S)-N-[(2S)-1-[(2-azanyl-2-oxo-ethyl)amino]-4-methyl-1-oxo-pentan-2-yl]pyrrolidine-2-carboxamide
- PRO-LEU-GLY AMIDE;MIF-I;OXYTOCIN FRAGMENT 7-9
- MSH-RELEASE INHIBITING FACTOR
- MELANOSTATIN
- (S)-N-((S)-1-((2-Amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
- MSH-R-IF
- Melanostatin I
- MIF-I, Melanostatin, Melanotropin Release-Inhibiting Factor
- PRO-LEU-GLY AMIDE
- Voir plus de synonymes
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5 produits concernés.
Melanocyte-Stimulating Hormone-Release Inhibiting Factor
CAS :MIF-I, the C-terminal tripeptide of oxytocin, has been shown to be active in numerous behavioral tests and clinical situations.Formule :C13H24N4O3Degré de pureté :> 99%Couleur et forme :WhiteMasse moléculaire :284.36H-PRO-LEU-GLY-NH2
CAS :Formule :C13H24N4O3Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :284.3547(S)-N-((S)-1-((2-Amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
CAS :Formule :C13H24N4O3Degré de pureté :95.0%Masse moléculaire :284.36MSH-Release Inhibiting Factor
CAS :<p>MSH-Release Inhibiting Factor (MRIF) has been shown to be a potent inhibitor of the release of proinflammatory cytokines. It is derived from the acid methyl ester of mouse serum, and has been shown to inhibit the release of tumor necrosis factor-α (TNF-α) in animal studies. MRIF has also been shown to have anti-diabetic effects in mice. MRIF inhibits the production of inflammatory cytokines by blocking TNF-α at a molecular level. This protein binds to progesterone receptor and prevents it from interacting with its ligand, which is necessary for cancer cell growth. The expression system for this protein is E. coli, and it can be used as an immunosuppressant in animal studies.<br>MRIF also blocks TNF-α activity by inhibiting transcriptional activation of NFκB and AP-1, which are proteins that regulate gene expression.</p>Formule :C13H24N4O3H2ODegré de pureté :Min. 95%Masse moléculaire :293.36 g/molMelanocyte-Stimulating Hormone-Release Inhibiting Factor
CAS :<p>Melanocyte-Stimulating Hormone-Release Inhibiting Factor (MSH-RF) is a synthetic peptide that inhibits the release of melanin from melanocytes. MSH-RF has been shown to be a useful treatment for melatonin deficiency, which may be related to immune system disorders such as infectious diseases and autoimmune diseases. It has also been shown to have significant interactions with other hormones such as dopamine, affecting locomotor activity and the ph optimum, among other biological properties. The structure of MSH-RF has been determined using X-ray crystallography on an amide bond. This peptide hormone is found in human serum and is involved in regulating camp levels.</p>Formule :C13H24N4O3Degré de pureté :Min. 95%Masse moléculaire :284.35 g/mol
