CAS 201410-66-4

(+)-Talarozole

CAS : 201410-66-4

Talarozole is a potent and selective inhibitor of human CYP3A4. It has been shown to inhibit the growth of inflammatory lesions in mice by inhibiting the production of inflammatory cytokines such as prostaglandin E2 (PGE2). Talarozole also inhibits the proliferation of hematopoietic cells, which are cells that produce all-trans retinoic acid (RA), a growth factor. The drug has been shown to reduce ventricular myocardial fatty acid content and increase fatty acid oxidation, which may reduce cardiac hypertrophy in rats.

Formule : C₂₁H₂₃N₅S

Degré de pureté : Min. 95%

Masse moléculaire : 377.5 g/mol

Ref: 3D-BIA41066