CAS 2029049-79-2

ML390

CAS : 2029049-79-2

ML390 exerts its potent differentiation effect on multiple leukemia models.

Formule : C₂₁H₂₁F₃N₂O₃

Degré de pureté : 99.76%

Couleur et forme : Solid

Masse moléculaire : 406.4

Ref: TM-T13774

N-[3-oxo-3-[[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]propyl]-4-(trifluoromethoxy)-benzamide

CAS : 2029049-79-2

Formule : C₂₁H₂₁F₃N₂O₃

Degré de pureté : 99%

Couleur et forme : Solid

Masse moléculaire : 406.3982

Ref: IN-DA01EPRB

ML390

CAS : 2029049-79-2

ML390

Degré de pureté : ≥98%

Masse moléculaire : 406.4g/mol

Ref: 54-BUP06140

ML390

CAS : 2029049-79-2

ML390 is a potent and selective inhibitor of the enzyme 3-phosphoglycerate dehydrogenase (3PGDH). This enzyme catalyzes the conversion of 3-phosphoglycerate to glyceraldehyde-3-phosphate, which is an important step in the synthesis of pyrimidine nucleotides. ML390 inhibits this enzyme with high selectivity and potency. It has been shown to be effective against glioblastoma cells, which may be due to its ability to inhibit their growth by targeting enzymes involved in pyrimidine biosynthesis.

Formule : C₂₁H₂₁F₃N₂O₃

Degré de pureté : Min. 95%

Masse moléculaire : 406.4 g/mol

Ref: 3D-EGD04979