CAS 2030410-25-2

PF 04449913 maleate

CAS : 2030410-25-2

PF 04449913 maleate is an analog of retinoic acid, which is used in human cancer therapy. It has been shown to inhibit the proliferation of leukemia stem cells and enhance the efficacy of radiation treatment. PF 04449913 maleate has also been shown to be effective against various other types of cancer, including prostate cancer. The mechanism of action is not clear but may involve inhibition of a pump that removes retinoic acid from the cell.

Formule : C₂₅H₂₆N₆O₅

Degré de pureté : Min. 95%

Masse moléculaire : 490.5 g/mol

Ref: 3D-FGD41025

PF 04449913 maleate

CAS : 2030410-25-2

Smo antagonist, IC50=5 nM; reduces AML cell leukemia potential and self-renewal in mice.

Formule : C₂₅H₂₆N₆O₅

Couleur et forme : Solid

Masse moléculaire : 490.52

Ref: TM-T36910