CAS 2059952-75-7

STAT3-IN-1

CAS : 2059952-75-7

STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and 2.14 μM , respectively), induces tumor

Formule : C₂₈H₂₉NO₆

Degré de pureté : 95.89% - 95.89%

Couleur et forme : Solid

Masse moléculaire : 475.53

Ref: TM-T13009

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

CAS : 2059952-75-7

Formule : C₂₈H₂₉NO₆

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 475.5330

Ref: IN-DA01KL6K

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

CAS : 2059952-75-7

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

Degré de pureté : 98%

Masse moléculaire : 475.53g/mol

Ref: 54-OR1023168

STAT3-IN-1

CAS : 2059952-75-7

STAT3-IN-1

Degré de pureté : ≥95%

Masse moléculaire : 475.53g/mol

Ref: 54-BUP08899

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

CAS : 2059952-75-7

Degré de pureté : ≥98%

Masse moléculaire : 475.5409851

Ref: 10-F864415

STAT3-IN-1

CAS : 2059952-75-7

STAT3-IN-1 is a small molecule that inhibits the activation of the transcription factor STAT3. STAT3 is involved in the regulation of cancer cell proliferation and survival, as well as the suppression of inflammation. STAT3-IN-1 has been shown to inhibit tumor growth by blocking IL-10 production and attenuating tissue inhibitor of metalloproteinase (TIMP)-1 expression. It also inhibits chemoresistance in breast cancer cells by reducing NF-κB activity, which leads to increased apoptosis and decreased proliferation rates. Additionally, STAT3-IN-1 has been shown to reduce tumor size in mice xenografts, enhance tissue regeneration and improve prognosis.

Formule : C₂₈H₂₉NO₆

Degré de pureté : Min. 95%

Masse moléculaire : 475.5 g/mol

Ref: 3D-JHD95275