CAS 206552-85-4

2'-O-Propargylcytidine

CAS : 206552-85-4

2'-O-Propargylcytidine is a novel nucleoside that has been modified from cytidine. It is designed to inhibit the activity of RNA polymerase and to be used in anticancer therapy. The synthesis of 2'-O-propargylcytidine has been achieved by modifying the nucleotide with propargylic chloride, which is then reacted with sodium cyanide. The resulting product is purified by column chromatography and recrystallization.
2'-O-Propargylcytidine is a phosphoramidite that can be used for DNA synthesis or as a monophosphate in RNA synthesis. This high purity product has a CAS number of 206552-85-4 and it can be used as an activator for ribonucleosides, such as adenosine, guanosine, uridine, cytidine, and thymidine.

Formule : C₁₂H₁₅N₃O₅

Degré de pureté : Min. 95%

Couleur et forme : Powder

Masse moléculaire : 281.26 g/mol

Ref: 3D-NP06202