CAS 2070015-25-5

EPZ020411 hydrochloride

CAS : 2070015-25-5

Formule : C₂₅H₃₉ClN₄O₃

Degré de pureté : 99%

Couleur et forme : Solid

Masse moléculaire : 479.0552

Ref: IN-DA01EO5Z

EPZ020411 hydrochloride

CAS : 2070015-25-5

EPZ020411 hydrochloride

Degré de pureté : ≥98%

Masse moléculaire : 479.05g/mol

Ref: 54-BUP08056

EPZ020411 hydrochloride

CAS : 2070015-25-5

EPZ020411 hydrochloride is a selective and potent small molecule PRMT6 inhibitor with an IC50 value of 10 nM.

Formule : C₂₅H₃₉ClN₄O₃

Degré de pureté : 99.88%

Couleur et forme : Solid

Masse moléculaire : 479.05

Ref: TM-T22325

EPZ020411 2HCl

CAS : 2070015-25-5

EPZ020411 2HCl is a chemical compound known as a potent selective inhibitor of the EZH2 methyltransferase, which is derived from enzymatic development processes involving high-throughput screening and medicinal chemistry optimization. With its mode of action centered on inhibiting the enzymatic activity of EZH2 (enhancer of zeste homolog 2), EPZ020411 2HCl effectively reduces the methylation of histone H3 on lysine 27 (H3K27), a critical process in gene expression regulation. This activity makes it an invaluable tool for studying epigenetic modifications and underlying oncogenic pathways.

The application of EPZ020411 2HCl is predominantly in the realm of cancer research, particularly in investigating the role of EZH2 in various malignancies, including prostate, breast, and hematopoietic cancers. By targeting and inhibiting EZH2, this compound aids in elucidating mechanisms of cancer progression, potentially leading to advancements in targeted therapeutic strategies. Additionally, it serves as a pivotal reference molecule in the structural and functional studies of histone methyltransferases, contributing to our broader understanding of epigenetic regulation.

Formule : C₂₅H₄₀Cl₂N₄O₃

Degré de pureté : Min. 95%

Masse moléculaire : 515.52 g/mol

Ref: 3D-VHD01525