CAS 2097497-16-8

(3Z)-1,3-Dihydro-5-hydroxy-4,6-dimethyl-3-(2-quinolinylmethylene)-2H-pyrrolo[2,3-b]pyridin-2-one

Formule : C₁₉H₁₅N₃O₂

Synonymes :

• (3Z)-1,3-Dihydro-5-hydroxy-4,6-dimethyl-3-(2-quinolinylmethylene)-2H-pyrrolo[2,3-b]pyridin-2-one

Anticancer agent 109

CAS : 2097497-16-8

Anticancer agent 109 (compound 6-15) acts as an inhibitor targeting the Gas6-Axl axis, demonstrating significant anti-cancer properties. This compound suppresses the expression of Gas6, Axl, p-PI3K, and p-AKT in cancer cells, thereby inducing G1 phase arrest and promoting apoptosis of cancer cells. Additionally, Anticancer agent 109 effectively inhibits tumor growth in nude mouse tumor-bearing models [1].

Formule : C₁₉H₁₅N₃O₂

Couleur et forme : Solid

Masse moléculaire : 317.34

Ref: TM-T85667