
CAS 2117404-84-7
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2 produits concernés.
BAY-677
CAS :BAY-677, an inactive counterpart to BAY-678, inhibits human neutrophil elastase with 20 nM IC50 and is an SGC-nominated probe.Formule :C20H15F3N4O2Couleur et forme :SolidMasse moléculaire :400.35BAY 677
CAS :<p>Bay 677 is a potent inhibitor of the human organic anion transporter (hOAT) that is currently being investigated for its effects on acute lung injury. Bay 677 has been shown to have a pharmacokinetic profile that is suitable for oral administration in humans, while methyl sulfone is metabolized through oxidative pathways. Bay 677 also has a high affinity for hOAT and disrupts the transport of organic anions across the cell membrane, which may be responsible for its anti-inflammatory effects.</p>Formule :C20H15F3N4O2Degré de pureté :Min. 95%Masse moléculaire :400.35 g/mol

