CAS 21215-62-3

calcitonine M

Description :

calcitonine M, identifié par le numéro CAS 21215-62-3, est un peptide synthétique qui imite l'hormone naturelle calcitonine, produite par la glande thyroïde. Cette substance est principalement connue pour son rôle dans la régulation des niveaux de calcium dans le corps en inhibant l'activité des ostéoclastes, réduisant ainsi la résorption osseuse et favorisant la formation osseuse. calcitonine M se caractérise par sa structure peptidique, qui consiste en une séquence spécifique d'acides aminés conférant son activité biologique. Il est généralement administré par injection et est utilisé dans des contextes cliniques pour traiter des conditions telles que l'ostéoporose et la maladie de Paget, où il est nécessaire d'augmenter la densité osseuse. Le peptide présente une demi-vie relativement courte dans la circulation, nécessitant un dosage et une administration soigneux. De plus, calcitonine M peut avoir des caractéristiques de stabilité et de solubilité variables selon sa formulation, ce qui peut influencer sa pharmacocinétique et son efficacité thérapeutique. Dans l'ensemble, calcitonine M représente un agent thérapeutique important dans la gestion des troubles liés aux os.

Formule : C₁₅₁H₂₂₆N₄₀O₄₅S₃

InChI : InChI=1/C151H228N40O45S3/c1-17-75(8)118(144(229)163-67-114(205)183-117(74(6)7)143(228)162-64-112(203)165-77(10)150(235)190-50-29-38-106(190)124(158)209)185-125(210)76(9)166-145(230)120(79(12)194)186-131(216)92(45-47-109(155)200)170-142(227)107-39-30-51-191(107)151(236)103(58-85-35-25-20-26-36-85)180-148(233)122(81(14)196)188-139(224)99(59-87-63-159-71-164-87)176-133(218)96(55-83-31-21-18-22-32-83)174-128(213)90(37-27-28-49-152)168-136(221)101(61-111(157)202)177-134(219)97(56-84-33-23-19-24-34-84)175-137(222)102(62-116(207)208)178-129(214)91(44-46-108(154)199)171-147(232)121(80(13)195)187-138(223)98(57-86-40-42-88(198)43-41-86)179-146(231)119(78(11)193)184-115(206)66-161-127(212)94(53-72(2)3)172-130(215)93(48-52-239-16)169-141(226)105(70-238)182-149(234)123(82(15)197)189-140(225)104(68-192)181-132(217)95(54-73(4)5)173-135(220)100(60-110(156)201)167-113(204)65-160-126(211)89(153)69-237/h18-26,31-36,40-43,63,71-82,89-107,117-123,192-198,237-238H,17,27-30,37-39,44-62,64-70,152-153H2,1-16H3,(H2,154,199)(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,209)(H,159,164)(H,160,211)(H,161,212)(H,162,228)(H,163,229)(H,165,203)(H,166,230)(H,167,204)(H,168,221)(H,169,226)(H,170,227)(H,171,232)(H,172,215)(H,173,220)(H,174,213)(H,175,222)(H,176,218)(H,177,219)(H,178,214)(H,179,231)(H,180,233)(H,181,217)(H,182,234)(H,183,205)(H,184,206)(H,185,210)(H,186,216)(H,187,223)(H,188,224)(H,189,225)(H,207,208)/t75-,76-,77-,78+,79+,80+,81+,82+,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,117-,118-,119-,120-,121-,122-,123-/m0/s1

Synonymes :

• Thyrocalcitonin Human
• Calcitonin human
• H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2 (Disulfide bond)

Calcitonin, human, 96%

CAS : 21215-62-3

For cellular and molecular biology applications

Degré de pureté : 96%

Couleur et forme : White, Powder

Ref: 02-J63192

Calcitonin (human)

CAS : 21215-62-3

Calcitonin is a peptide hormone involved in calcium and phosphorus homeostasis. Its inhibitory effect on osteoclast activity lowers blood calcium levels and positively influences bone mass density.

Formule : C₁₅₁H₂₂₆N₄₀O₄₅S₃

Degré de pureté : 96.1%

Couleur et forme : White

Masse moléculaire : 3417.9

Ref: 01-4014409

Calcitonin (human)

CAS : 21215-62-3

Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.

Formule : C₁₅₁H₂₂₆N₄₀O₄₅S₃

Degré de pureté : 98%

Couleur et forme : White Lyophilized Powder

Masse moléculaire : 3417.87

Ref: TM-TP2055

Calcitonin (Human)

CAS : 21215-62-3

Calcitonin is a hormone produced by the C cells (also known as parafollicular cells) in the thyroid gland. Its main function is to regulate the levels of calcium and phosphate in the blood. Calcitonin works by inhibiting the activity of osteoclasts, which are cells that break down bone tissue and release calcium and phosphate into the bloodstream. This leads to a decrease in the amount of calcium and phosphate in the blood.
Calcitonin is released in response to high levels of calcium in the blood, and it acts to reduce these levels by increasing the excretion of calcium by the kidneys and inhibiting the absorption of calcium by the intestines. It also promotes the storage of calcium in the bones, which helps to maintain their strength and density.
Calcitonin may be used therapeutically to treat conditions such as osteoporosis and hypercalcemia (high levels of calcium in the blood) or even diagnostically as a marker for tumors in medullary thyroid cancer.
This product has a disulfide bond between Cys1-Cys7 and is available as a 0.1mg vial.

Formule : C₁₅₁H₂₂₆N₄₀O₄₅S₃

Degré de pureté : Min. 95%

Masse moléculaire : 3,417.8 g/mol

Ref: 3D-PCL-4051-S

Calcitonin (Human)

CAS : 21215-62-3

Calcitonin is a hormone produced by the C cells (also known as parafollicular cells) in the thyroid gland. Its main function is to regulate the levels of calcium and phosphate in the blood. Calcitonin works by inhibiting the activity of osteoclasts, which are cells that break down bone tissue and release calcium and phosphate into the bloodstream. This leads to a decrease in the amount of calcium and phosphate in the blood.
Calcitonin is released in response to high levels of calcium in the blood, and it acts to reduce these levels by increasing the excretion of calcium by the kidneys and inhibiting the absorption of calcium by the intestines. It also promotes the storage of calcium in the bones, which helps to maintain their strength and density.
Calcitonin may be used therapeutically to treat conditions such as osteoporosis and hypercalcemia (high levels of calcium in the blood) or even diagnostically as a marker for tumors in medullary thyroid cancer.
This product has a disulfide bond between Cys1-Cys7 and is available as a 0.5mg vial.

Formule : C₁₅₁H₂₂₆N₄₀O₄₅S₃

Degré de pureté : Min. 95%

Masse moléculaire : 3,417.8 g/mol

Ref: 3D-PCL-4051-V

Calcitonin (human) trifluoroacetate salt

CAS : 21215-62-3

Trifluoroacetate salt

Formule : C₁₅₁H₂₂₆N₄₀O₄₅S₃

Degré de pureté : Min. 95%

Masse moléculaire : 3,417.85 g/mol

Ref: 3D-FC108641

CALCITONIN, HUMAN

CAS : 21215-62-3

Formule : C₁₅₁H₂₂₆N₄₀O₄₅S₃

Degré de pureté : 97%

Couleur et forme : Solid

Masse moléculaire : 3417.846139999987

Ref: IN-DA00BC5X