CAS 2130958-55-1

N-[2-[[2-(Dimethylamino)ethyl]methylamino]-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-2-propenamide methanesulfonate

CAS : 2130958-55-1

Formule : C₂₉H₃₅F₃N₈O₅S

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 664.6990

Ref: IN-DA01EO87

N-(2-((2-(Dimethylamino)Ethyl)(Methyl)Amino)-5-((4-(1-Methyl-1H-Indol-3-Yl)Pyrimidin-2-Yl)Amino)-6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl)Acrylamide Methanesulfonate

CAS : 2130958-55-1

N-(2-((2-(Dimethylamino)Ethyl)(Methyl)Amino)-5-((4-(1-Methyl-1H-Indol-3-Yl)Pyrimidin-2-Yl)Amino)-6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl)Acrylamide Methanesulfonate

Degré de pureté : 99%

Masse moléculaire : 664.7g/mol

Ref: 54-PC108568

Alflutinib mesylate

CAS : 2130958-55-1

Alflutinib mesylate

Degré de pureté : ≥95%

Masse moléculaire : 664.7g/mol

Ref: 54-BUP07742

Alflutinib mesylate

CAS : 2130958-55-1

Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.

Formule : C₂₉H₃₅F₃N₈O₅S

Degré de pureté : 97.94% - 99.63%

Couleur et forme : Solid

Masse moléculaire : 664.7

Ref: TM-T7175

Ast2818 mesylate

CAS : 2130958-55-1

Ast2818 mesylate is a small-molecule, orally active, selective factor receptor tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR) and its downstream signaling proteins. Ast2818 mesylate binds to the EGFR at a site distinct from the ATP binding site and prevents phosphorylation by protein tyrosine kinases. It inhibits cell proliferation by blocking the activation of downstream signaling proteins such as Ras, Raf, and Akt. The compound has been evaluated in preclinical studies for potential use as an antineoplastic agent in lung cancer. In these studies, Ast2818 mesylate inhibited tumor growth in mouse models of lung cancer. Further analysis showed that this effect was due to inhibition of epidermal growth factor receptor-mediated signaling pathways involved in cell proliferation and tumorigenesis.

Formule : C₂₉H₃₅F₃N₈O₅S

Degré de pureté : Min. 95%

Masse moléculaire : 664.7 g/mol

Ref: 3D-FKD95855