CAS 2141974-01-6

Benzenepropanamine, 4-methoxy-N-[(1S)-1-methyl-2-phenylethyl]-

Formule : C₁₉H₂₅NO

Synonymes :

• Benzenepropanamine, 4-methoxy-N-[(1S)-1-methyl-2-phenylethyl]-

GZ-11608

CAS : 2141974-01-6

GZ-11608, a selective and potent inhibitor of vesicular monoamine transporter-2 (VMAT2), presents a high affinity with a Ki value of 25 nM. It effectively reduces dopamine release induced by methamphetamine from isolated synaptic vesicles in brain dopaminergic neurons. GZ-11608 also demonstrates rapid penetration into the brain without exhibiting neurotoxicity, making it a valuable compound for researching methamphetamine use disorder [1].

Formule : C₁₉H₂₅NO

Couleur et forme : Solid

Masse moléculaire : 283.41

Ref: TM-T86539