CAS 2206825-87-6

Apixaban Open Chain Acid Impurity

CAS : 2206825-87-6

Formule : C₂₅H₂₇N₅O₅

Couleur et forme : Pale Yellow Solid

Masse moléculaire : 477.52

Ref: 4Z-A-10221

5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoic acid

CAS : 2206825-87-6

5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoic acid

Degré de pureté : 97%

Masse moléculaire : 477.52g/mol

Ref: 54-OR1074245

5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic Acid

CAS : 2206825-87-6

Couleur et forme : Neat

Ref: 86-MM3754.04

Apixaban Amino Acid Impurity

CAS : 2206825-87-6

Formule : C₂₅H₂₇N₅O₅

Masse moléculaire : 477.52

Ref: ST-EA-CP-A3009

5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic Acid

CAS : 2206825-87-6

Applications Apixaban Open chain Acid Is an open ring impurity of Apixaban (A726700). Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);

Formule : C₂₅H₂₇N₅O₅

Couleur et forme : Light Yellow

Masse moléculaire : 477.51

Ref: TR-A875620