CAS 2213490-89-0

SR 19881

CAS : 2213490-89-0

SR 19881

Degré de pureté : ≥95%

Masse moléculaire : 312.41g/mol

Ref: 54-BUP04377

SR 19881

CAS : 2213490-89-0

SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).

Formule : C₁₉H₂₄N₂O₂

Degré de pureté : 98.54%

Couleur et forme : Solid

Masse moléculaire : 312.41

Ref: TM-T7904

N-(4-(Diethylamino)phenethyl)-4-hydroxybenzamide

CAS : 2213490-89-0

N-(4-(Diethylamino)phenethyl)-4-hydroxybenzamide (NDEA) is a drug that inhibits the enzyme 11β-hydroxysteroid dehydrogenase type 1, which converts cortisone to cortisol. It has been used in clinical trials for the treatment of acute and chronic inflammatory diseases, such as rheumatoid arthritis and ulcerative colitis. NDEA has been shown to inhibit the proliferation of neural progenitor cells in culture, thereby causing a decrease in neurogenesis. This effect may be due to its ability to inhibit glucocorticoid receptors on neural stem cells. This molecule also inhibits cell proliferation in cultured mouse hippocampal neurons.

Formule : C₁₅H₁₂ClN₃O

Degré de pureté : Min. 95%

Masse moléculaire : 285.73 g/mol

Ref: 3D-NND49089