CAS 222412-87-5

Atorvastatin-d5 Sodium Salt

Produit contrôlé

CAS : 222412-87-5

Stability Hygroscopic
Applications A deuterated selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),

Formule : C₃₃₂H₅H₂₉FN₂O₅·Na

Degré de pureté : >90%

Couleur et forme : Off-White To Light Brown

Masse moléculaire : 585.65

Ref: TR-A791752

Atorvastatin-d5 sodium

CAS : 222412-87-5

Atorvastatin-d5 sodium is an isotopically labeled pharmaceutical compound, which is derived from atorvastatin by incorporating deuterium atoms. This synthetic modification is essential for tracing and quantification in pharmacokinetic studies. As a statin, its mode of action involves the selective inhibition of the enzyme HMG-CoA reductase, a crucial catalyst in the mevalonate pathway responsible for cholesterol biosynthesis in the liver. By inhibiting this enzyme, atorvastatin-d5 effectively lowers the production of low-density lipoprotein (LDL) cholesterol.

Formule : C₃₃H₃₀D₅FN₂O₅·Na

Degré de pureté : Min. 95%

Masse moléculaire : 586.66 g/mol

Ref: 3D-XIA41287