CAS 2243701-11-1

Dyrk1A-IN-12

CAS : 2243701-11-1

Dyrk1A-IN-12 (compound S43) is an inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1A). It has an IC50 of 95 nM for inhibiting Dyrk1A. The compound demonstrates antiviral activity against EV-A71 (Enterovirus A71) with an EC50 of 4.4 μM, a CC50 of 12.8 μM, and a selectivity index (SI) of 2.9. Additionally, Dyrk1A-IN-12 exhibits potent inhibitory effects on the herpes simplex virus (HSV).

Formule : C₂₂H₁₆FN₃O₂S

Couleur et forme : Solid

Masse moléculaire : 405.445

Ref: TM-T205530