CAS 2247543-65-1

WS 383

CAS : 2247543-65-1

Potent inhibitor of the interaction between defective cullin neddylation protein DCN1 and NEDD8-conjugating enzyme UBC12 with IC50 of 11 nM. WS 383 blocks the DCN1-UBC12 interaction in a reversible manner, selectively inhibits Cul3/1 neddylation and induces accumulation of p21, p27, and NRF2 proteins.

Formule : C₁₈H₂₀ClN₉S₂

Degré de pureté : Min. 95%

Masse moléculaire : 462 g/mol

Ref: 3D-BW168424

WS-383 free base

CAS : 2247543-65-1

WS-383 free base is a selective and reversible DCN1-UBC12 interaction inhibitor(IC50 of 11 nM).

Formule : C₁₈H₂₀ClN₉S₂

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 461.99

Ref: TM-T13348