CAS 2252395-44-9

J22352

CAS : 2252395-44-9

J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects in

Formule : C₂₄H₂₁N₃O₄

Couleur et forme : Solid

Masse moléculaire : 415.44

Ref: TM-T11701

J22352

CAS : 2252395-44-9

J22352 is an inhibitor of cyclin-dependent kinases, a group of enzymes that play a crucial role in regulating cell division. It has shown strong anticancer activity against human cancer cells in vitro and in vivo. J22352 induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of specific proteins involved in cell survival pathways. This compound is an analog of a natural product isolated from Chinese medicinal plants and has been shown to have potent kinase inhibitory activity. J22352 may be a promising candidate for the development of new anticancer drugs with improved efficacy and fewer side effects. Additionally, this compound can be detected in urine samples, making it a potential biomarker for cancer diagnosis and treatment monitoring.

Formule : C₂₄H₂₁N₃O₄

Degré de pureté : Min. 95%

Masse moléculaire : 415.4 g/mol

Ref: 3D-CQD39544