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CAS 2265899-49-6

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1 produits concernés.
  • ORN0829
    Biosynth
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    ORN0829

    CAS :
    <p>ORN0829 is a novel, orally active, potent, and selective antagonist of serotonin 5-HT2A receptors. ORN0829 has been shown to inhibit the growth of human cancer cells in vitro and in vivo with a side-effect profile that is significantly less than other 5-HT2A antagonists currently in clinical development. ORN0829 also inhibits the binding of serotonin to 5-HT2A receptors and blocks the downstream signaling pathways of phospholipase C, protein kinase C, and mitogen-activated protein kinases.<br>ORN0829 has an onset latency time of about 1 hour and its pharmacokinetic properties have been evaluated in both mice and rats. In these studies, ORN0829 was found to be well tolerated with no observed adverse effects.</p>
    Formule :C23H22FN7O2
    Degré de pureté :Min. 95%
    Masse moléculaire :447.47 g/mol

    Ref: 3D-BO177707

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