CAS 2315450-35-0

Kv7.2/Kv7.3 agonist 1

CAS : 2315450-35-0

Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally effective agonist for the KV7.2/7.3 channels (KV7.2/7.3 channel/KCNQ2/3) with an EC50 of 1.03 μM. This compound demonstrates analgesic effects in mouse models of chronic constriction injury (CCI) and Streptozotocin-induced diabetic peripheral neuropathy (DPNP), with ED50 values of 12.02 mg/kg and 9.63 mg/kg, respectively.

Formule : C₁₄H₁₄FN₃O₂

Couleur et forme : Solid

Masse moléculaire : 275.28

Ref: TM-T201063