CAS 2351820-19-2

GK 563

CAS : 2351820-19-2

Potent inhibitor of the calcium-independent phospholipase A2 (GVIA iPLA2) with IC50 of 1 nM. GK 563 is 22000 times more active against GVIA iPLA2 than against the cytoplasmic phospholipase GVIA cPLA2. In β pancreatic cells from rat, GK 563 was shown to inhibit the β cell apoptosis when co-administered with pro-inflammatory cytokines.

Formule : C₁₆H₂₂O₂

Degré de pureté : Min. 95%

Couleur et forme : Solid

Masse moléculaire : 246.34 g/mol

Ref: 3D-BG168610

GK563

CAS : 2351820-19-2

GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.

Formule : C₁₆H₂₂O₂

Couleur et forme : Solid

Masse moléculaire : 246.34

Ref: TM-T73527