CAS 2365172-19-4

4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-(((15R)-1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-12-methyl-16-(phenylthio)-3,6

CAS : 2365172-19-4

4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-(((15R)-1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-12-methyl-16-(phenylthio)-3,6

Degré de pureté : 98%

Masse moléculaire : 1350.01g/mol

Ref: 54-PC1007694

XZ739

CAS : 2365172-19-4

XZ739: Cereblon-based PROTAC, degrades BCL-XL (DC50 2.5 nM in MOLT-4, 16hr), induces caspase apoptosis.

Formule : C₆₅H₇₆ClF₃N₈O₁₂S₃

Couleur et forme : Solid

Masse moléculaire : 1349.99

Ref: TM-T39909

XZ739

CAS : 2365172-19-4

XZ739 is a peptidomimetic inhibitor of the phosphatase calcineurin. It has been shown to activate the transcription factor NFAT in cells, leading to increased cellular proliferation and inhibition of apoptosis. XZ739 has also been shown to have a potent inhibitory effect on the activity of protein tyrosine phosphatases, which are involved in signal transduction pathways. This agent is synthesized in high purity and can be used as a research tool for studying protein interactions and receptor ligand binding.

Formule : C₆₅H₇₆ClF₃N₈O₁₂S₃

Degré de pureté : Min. 95%

Masse moléculaire : 1,350 g/mol

Ref: 3D-QUD17219