CAS 2375815-63-5

(2R,3R,4S)-3-Acetamido-4-guanidino-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylic acid hydrate

CAS : 2375815-63-5

Formule : C₁₅H₁₈N₄O₂

Degré de pureté : 97%

Couleur et forme : Solid

Masse moléculaire : 286.3290

Ref: IN-DA01K2R8

CD73-IN-3

CAS : 2375815-63-5

CD73-IN-3

Degré de pureté : ≥98%

Masse moléculaire : 286.33g/mol

Ref: 54-BUP08223

CD73-IN-3

CAS : 2375815-63-5

CD73-IN-3 (LY-3475070) is a potent CD73 inhibitor with a 28 nM IC50, being tested in advanced cancer alone or with pembrolizumab.

Formule : C₁₅H₁₈N₄O₂

Degré de pureté : 99.76%

Couleur et forme : Solid

Masse moléculaire : 286.33

Ref: TM-T8875

5-(5-((1S,2R)-2-Isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione

CAS : 2375815-63-5

5-(5-((1S,2R)-2-Isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione is a potent and selective inhibitor of the neuronal Kv7.2 potassium channel. It binds to the central pore region of the Kv7.2 channel and blocks activation by extracellular potassium ions. This inhibition prevents depolarization of neurons and reduces neuronal excitability, which may be responsible for its analgesic effect. 5-(5-((1S,2R)-2-Isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione has been shown to reduce pain in animal studies and is being developed as a potential treatment for neuropathic pain.

Formule : C₁₅H₁₈N₄O₂

Degré de pureté : Min. 95%

Masse moléculaire : 286.33 g/mol

Ref: 3D-AVD81563