CAS 24280-93-1
:Acide mycophénolique
Description :
Acide mycophénolique est un composé organique avec la formule chimique C17H20O6 et est classé comme un immunosuppresseur sélectif. Il est principalement dérivé du champignon Penicillium et est connu pour son rôle dans l'inhibition de l'enzyme inosine monophosphate déshydrogénase (IMPDH), qui est cruciale dans la voie de synthèse de novo des nucléotides puriques. Ce mécanisme le rend particulièrement efficace pour prévenir le rejet de greffe d'organes et traiter les maladies auto-immunes. Acide mycophénolique apparaît sous forme de poudre cristalline blanche à blanc cassé et est soluble dans des solvants organiques comme l'éthanol et le diméthylsulfoxyde, mais a une solubilité limitée dans l'eau. Ses propriétés pharmacologiques incluent des effets anti-inflammatoires, et il est souvent utilisé en combinaison avec d'autres immunosuppresseurs pour améliorer l'efficacité et réduire le risque de rejet chez les patients transplantés. Cependant, il peut également entraîner des effets secondaires tels que des troubles gastro-intestinaux et un risque accru d'infections en raison de son action immunosuppressive. Une surveillance appropriée et des ajustements de dosage sont essentiels pendant son utilisation thérapeutique.
Formule :C17H20O6
InChI :InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+
Code InChI :InChIKey=HPNSFSBZBAHARI-RUDMXATFSA-N
SMILES :CC1=C2C(=C(O)C(C/C=C(/CCC(O)=O)\C)=C1OC)C(=O)OC2
Synonymes :- (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid
- (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
- (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
- (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid
- 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-
- 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
- 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)-
- 6-(4-Hydroxy-6-Methoxy-7-Methyl-3-Oxo-1,3-Dihydro-2-Benzofuran-5-Yl)-4-Methylhex-4-Enoic Acid
- Acide Mycophenolique
- Acido Micofenolico
- Lilly 68618
- MPA
- Melbex
- Mycophenolic Acid From Penicillium Brevi-Compactum
- Mycophenolic Acid From Penicillium*Brevi-Compactu
- Mycophenolinsaure
- Nsc 129185
- Voir plus de synonymes
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19 produits concernés.
Mycophenolic Acid
CAS :Formule :C17H20O6Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :320.34Mycophenolic acid, 98%
CAS :<p>It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly</p>Formule :C17H20O6Degré de pureté :98%Masse moléculaire :320.344-Hexenoic acid,6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-
CAS :Formule :C17H20O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :320.3371Ref: IN-DA00I4O6
1g26,00€5g29,00€10g44,00€1kg524,00€25g49,00€5kgÀ demander75g103,00€100g116,00€200g189,00€300g201,00€400g264,00€500g281,00€Mycophenolic acid
CAS :Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.Formule :C17H20O6Degré de pureté :98.79% - 99.77%Couleur et forme :SolidMasse moléculaire :320.34Mycophenolic Acid (Mycophenolate Mofetil EP Impurity F)
CAS :Formule :C17H20O6Couleur et forme :White To Off-White SolidMasse moléculaire :320.34Mycophenolic acid
CAS :Formule :C17H20O6Degré de pureté :≥ 98.0%Couleur et forme :White to off-white crystalline powderMasse moléculaire :320.34Mycophenolic acid 100 µg/mL in Acetonitrile
CAS :Produit contrôléFormule :C17H20O6Couleur et forme :Single SolutionMasse moléculaire :320.34Mycophenolic acid
CAS :Produit contrôléFormule :C17H20O6Couleur et forme :NeatMasse moléculaire :320.34Mycophenolic Acid
CAS :Produit contrôlé<p>Applications An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.Environmental contaminants; Food contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),<br></p>Formule :C17H20O6Couleur et forme :White To Off-WhiteMasse moléculaire :320.34Mycophenolic acid - Bio-X ™
CAS :<p>Mycophenolic acid is an immunosuppressant metabolite present in drug formulations that are used to prevent rejections after organ transplants. Mycophenolic acid is a selective inhibitor of inosine monophosphate dehydrogenase (IMPDH) which blocks the conversion of inosine-5-phosphate and xanthine-5-phosphate to guanosine-5-phosphate. This drug inhibits de novo purine biosynthesis. It has also shown to have antibacterial and antifungal properties.</p>Formule :C17H20O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :320.34 g/molMycophenolic acid
CAS :<p>Mycophenolic acid is a guanosine monophosphate synthesis pathway blocker. It selectively inhibits inosine monophosphate dehydrogenase (IMPDH) which blocks the conversion of inosine-5-phosphate and xanthine-5-phosphate to guanosine-5-phosphate. This drug inhibits de novo purine biosynthesis. Mycophenolic acid is an immunosuppressant metabolite present in drug formulations that are used to prevent rejections after organ transplants. It has also shown to have antibacterial and antifungal properties.</p>Formule :C17H20O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :320.34 g/molMycophenolic Acid
CAS :<p>M02087 - Mycophenolic Acid</p>Formule :C17H20O6Degré de pureté :98%Couleur et forme :Solid, White to off-white powderMasse moléculaire :320.341Mycophenolic Acid-13C-d3
CAS :Produit contrôlé<p>Applications Mycophenolic Acid-13C-d3 is a labelled Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.<br>References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),<br></p>Formule :CC16D3H17O6Couleur et forme :NeatMasse moléculaire :324.348Mycophenolic Acid ((4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid)
CAS :Aromatic lactones used as drugsFormule :C17H20O6Couleur et forme :White Crystalline SolidMasse moléculaire :320.12599
