CAS 252642-12-9

L-Phénylalanine, L-leucyl-L-valyl-L-glutaminyl-L-prolyl-L-arginylglycyl-L-sérinyl-L-arginyl-L-asparaginylglycyl-L-prolylglycyl-L-prolyl-L-tryptophyl-L-glutaminylglycylglycyl-L-arginyl-L-arginyl-L-lysyl-L-phénylalaninyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl

Description :

La substance à laquelle vous faites référence, portant le nom "L-Phénylalanine, L-leucyl-L-valyl-L-glutaminy-L-prolyl-L-arginylglycyl-L-sérin-L-arginyl-L-asparaginylglycyl-L-prolylglycyl-L-prolyl-L-tryptophyl-L-glutaminyglycylglycyl-L-arginyl-L-arginyl-L-lysyl-L-phénylalaniny-L-arginyl-L-arginyl-L-glutaminy-L-arginine" et numéro CAS "252642-12-9", est un peptide complexe composé de plusieurs acides aminés. Ce composé est caractérisé par sa séquence d'acides aminés, qui comprend des acides aminés essentiels et non essentiels, contribuant à son activité biologique potentielle. Les peptides comme celui-ci peuvent jouer des rôles significatifs dans divers processus physiologiques, y compris la régulation hormonale, la réponse immunitaire et la neurotransmission. La présence de multiples résidus d'arginine et de glycine suggère un potentiel d'interaction avec des récepteurs biologiques ou des enzymes. De plus, la solubilité, la stabilité et la réactivité du peptide peuvent être influencées par sa composition et sa séquence d'acides aminés, ce qui peut affecter ses applications dans des contextes de recherche ou thérapeutiques. Dans l'ensemble, cette substance représente une structure complexe qui peut avoir des propriétés biochimiques uniques.

Formule : C₁₈₄H₂₉₇N₆₉O₄₃S

Synonymes :

• Apelin(human)

Apelin-36 (human)

CAS : 252642-12-9

The orphan G protein-coupled receptor APJ has been shown to be a coreceptor for human and simian immunodeficiency virus (HIV and SIV) strains. As long as apelin is an endogenous ligand for the APJ receptor, inhibitory effects of apelin peptides on HIV infection have been examined and it has been found that the apelin peptides inhibit the entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ. For apelin-36 the strongest inhibitory efficiency has been reported.

Formule : C₁₈₄H₂₉₇N₆₉O₄₃S

Degré de pureté : > 96%

Couleur et forme : White Powder

Masse moléculaire : 4195.89

Ref: 01-4034005

Apelin 36

CAS : 252642-12-9

Formule : C₁₈₄H₂₉₇N₆₉O₄₃S

Degré de pureté : 98%

Masse moléculaire : 4195.8285

Ref: IN-DA0039XR

Apelin-36(human)

CAS : 252642-12-9

Endogenous APJ agonist, EC50=20nM, regulates cardiovascular function, fluid balance, and feeding; blocks certain HIV strains.

Formule : C₁₈₄H₂₉₇N₆₉O₄₃S

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 4195.87

Ref: TM-TP2093

Apelin-36 Human

CAS : 252642-12-9

Apelin-36 (human) is derived from the apelin peptide which acts as a ligand for the apelin receptor (APJ) G protein coupled receptor and is a substrate for angiotensin converting enzyme 2. Preprapelin, encoded for by APLN located on Xq25-26.1, is cleaved to form either apelin 36, apelin 17, apelin 13, or apelin 12. As a member of the adipokine hormone family, which are involved in processes such as vascular homeostasis and angiogenesis, apelin is secreted from adipose tissue.Both apelin and the apelin receptor are widely distributed around the body thus apelin has been found to be associated with cardiovascular diseases, obesity, diabetes and cancer. Studies exploring myocardial infarction showed there to be greater apelin mRNA expression during human heart failure compared to in healthy tissue. Apelin protects against heart failure due to, the pyroglutamyl form of apelin, playing a role in decreasing infarct size of myocardial infarctions. Furthermore in rats with hypertension, the expression of apelin and APJ was decreased.

Masse moléculaire : 4,193.3 g/mol

Ref: 3D-CRB1000048

Apelin-36

CAS : 252642-12-9

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formule : C₁₈₄H₂₉₇N₆₉O₄₃S

Masse moléculaire : 4,195.9 g/mol

Ref: 3D-PP50521

H-LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF-OH

CAS : 252642-12-9

Peptide H-LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Masse moléculaire : 4,195.89 g/mol

Ref: 3D-PP49914

Apelin-36, human

CAS : 252642-12-9

Custom research peptide; min purity 95%.

Formule : C₁₈₄H₂₉₇N₆₉O₄₃S

Degré de pureté : Min. 95%

Masse moléculaire : 4,195.92 g/mol

Ref: 3D-PA16915

Apelin-36 (Human)

CAS : 252642-12-9

Apelin-36 is a peptide hormone that is derived from a larger precursor protein. It is a member of the apelin peptide family, which is involved in regulating cardiovascular and metabolic functions.
Apelin-36 binds to a G protein-coupled receptor called APJ (apelin receptor), which is widely expressed in various tissues. The interaction between apelin-36 and APJ receptor leads to a range of physiological effects, such as cardiac contractility stimulation and blood pressure suppression as well as lowering body weight and improving glucose homeostasis.
Research has shown that apelin-36 may have therapeutic potential in the treatment of cardiovascular diseases, such as hypertension and heart failure, as well as metabolic disorders, such as obesity and diabetes. Apelin-36 has also been implicated in other physiological processes, including inflammation, angiogenesis, and cancer progression. This product is available as a 0.1 mg vial.

Formule : C₁₈₄H₂₉₇N₆₉O₄₃S

Degré de pureté : Min. 95%

Masse moléculaire : 4,195.8 g/mol

Ref: 3D-PAP-4362-S

Apelin-36 (human)

CAS : 252642-12-9

Apelin-36 is a human apelin protein. It is involved in the regulation of appetite and energy expenditure. Apelin-36 has been shown to be an independent predictor of body mass index and insulin resistance in women with polycystic ovary syndrome. Apelin-36 is also an indicator of the risk for cardiovascular disease, stroke, and type 2 diabetes mellitus. This molecule can be measured using a Western blot assay method on ovary homogenates. The level of apelin-36 can be used as a diagnostic tool for determining insulin resistance and overweight status.

Formule : C₁₈₄H₂₉₇N₆₉O₄₃S

Degré de pureté : Min. 95%

Masse moléculaire : 4,195.83 g/mol

Ref: 3D-FA109395