CAS 256476-36-5

UK-371804 HCl

CAS : 256476-36-5

Formule : C₁₄H₁₇Cl₂N₅O₄S

Degré de pureté : 97%

Couleur et forme : Solid

Masse moléculaire : 422.2869

Ref: IN-DA01FG01

UK-371804 HCl

CAS : 256476-36-5

UK-371804 is a toolbox prodrug that is designed to inhibit serine proteases. It can be used as a prognostic marker or as a drug to treat various diseases such as cancer and cardiovascular disease. UK-371804 binds to the active site of the serine protease and inhibits its activity, leading to decreased production of inflammatory cytokines. This drug has been shown in vitro to have potent anti-angiotensin converting enzyme (ACE) activity. UK-371804 HCl has also been shown in vivo to inhibit plasminogen activator, which is necessary for fibrinolysis and blood clot dissolution. The enzyme, plasminogen activator, is inhibited by blocking its binding site on the surface of the endothelial cells with an integrin receptor blocker.

Formule : C₁₄H₁₆ClN₅O₄S·HCl

Degré de pureté : Min. 95%

Masse moléculaire : 422.29 g/mol

Ref: 3D-GKA47636

UK-371804 HCl

CAS : 256476-36-5

UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-

Formule : C₁₄H₁₇Cl₂N₅O₄S

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 422.29

Ref: TM-T22451