CAS 257892-33-4

N-(3,5-Dichloro-4-Pyridinyl)-2-[1-(4-Fluorobenzyl)-5-Hydroxy-1H-Indol-3-Yl]-2-Oxoacetamide

Produit contrôlé

CAS : 257892-33-4

N-(3,5-Dichloro-4-Pyridinyl)-2-[1-(4-Fluorobenzyl)-5-Hydroxy-1H-Indol-3-Yl]-2-Oxoacetamide is a prodrug that is metabolized to the active form in vivo. It inhibits the activity of cyclic nucleotide phosphodiesterase (PDE), an enzyme that catalyzes the conversion of cAMP to AMP and PDE, which catalyzes the conversion of cGMP to GMP. This drug has been shown to have a potent inhibitory effect on inflammatory cytokines such as IL-6 and TNFα. N-(3,5-Dichloro-4-pyridinyl)-2-[1-(4 fluorobenzyl)-5 hydroxy 1H indol 3 yl]-2 oxoacetamide has been shown to be effective for treatment of inflammatory diseases such as bronch

Formule : C₂₂H₁₄Cl₂FN₃O₃

Degré de pureté : Min. 95%

Masse moléculaire : 458.27 g/mol

Ref: 3D-FD101748

AWD 12-281

CAS : 257892-33-4

AWD 12-281 is a PDE4 inhibitor with anti-inflammatory activity and bronchodilator activity for the study of chronic obstructive pulmonary disease (COPD).

Formule : C₂₂H₁₄Cl₂FN₃O₃

Degré de pureté : 99.25% - 99.85%

Couleur et forme : Solid

Masse moléculaire : 458.27

Ref: TM-T30232