CAS 258864-18-5

3-Fluoro-5-morpholinoaniline

CAS : 258864-18-5

Formule : C₁₀H₁₃FN₂O

Couleur et forme : Solid

Masse moléculaire : 196.2214

Ref: IN-DA01A8BV

3-Fluoro-5-(morpholin-4-yl)aniline

CAS : 258864-18-5

3-Fluoro-5-(morpholin-4-yl)aniline is a synthetic compound that has been shown to inhibit the growth of bacteria by binding to the enzyme dihydropteroate synthase. This drug inhibits bacterial growth by preventing the formation of folic acid, which is essential for DNA synthesis. 3-Fluoro-5-(morpholin-4-yl)aniline has also been shown to be selective against other enzymes in the folate pathway, such as thymidylate synthase and glycinamide ribonucleotide formyltransferase. Theoretical studies suggest that 3-fluoro-5-(morpholin-4-yl)aniline binds to the substrate binding site on dihydropteroate synthase and sterically hinders access to substrates in this region of the enzyme. Density functional theory calculations show that this compound binds more tightly than a number of natural products. Intramolecular

Formule : C₁₀H₁₃FN₂O

Degré de pureté : Min. 95%

Couleur et forme : Powder

Masse moléculaire : 196.22 g/mol

Ref: 3D-IKA86418