CAS 27215-14-1
:Néoandrographolide
Description :
Néoandrographolide est un composé naturel dérivé de la plante Andrographis paniculata, communément connu pour ses propriétés médicinales. Il appartient à la classe des diterpénoïdes et se caractérise par sa structure bicyclique complexe, qui contribue à son activité biologique. Ce composé présente une gamme d'effets pharmacologiques, y compris des propriétés anti-inflammatoires, antioxydantes et antimicrobiennes. Néoandrographolide a été étudié pour ses applications thérapeutiques potentielles, en particulier dans le traitement de diverses maladies, y compris les infections et les conditions inflammatoires. Son mécanisme d'action implique souvent la modulation des voies de signalisation et l'inhibition des cytokines pro-inflammatoires. De plus, il est connu pour posséder des effets hépatoprotecteurs, ce qui en fait un sujet d'intérêt dans la recherche sur la santé du foie. Le composé est généralement extrait des feuilles de la plante Andrographis et peut être analysé à l'aide de diverses techniques telles que la chromatographie et la spectroscopie pour confirmer sa pureté et sa concentration. Dans l'ensemble, Néoandrographolide représente un domaine d'intérêt significatif en chimie des produits naturels et en pharmacologie en raison de ses diverses activités biologiques et de ses avantages potentiels pour la santé.
Formule :C26H40O8
InChI :InChI=1/C26H40O8/c1-15-5-8-19-25(2,14-33-24-22(30)21(29)20(28)18(13-27)34-24)10-4-11-26(19,3)17(15)7-6-16-9-12-32-23(16)31/h9,17-22,24,27-30H,1,4-8,10-14H2,2-3H3/t17-,18-,19-,20-,21+,22-,24-,25+,26+/m1/s1
Code InChI :InChIKey=YGCYRQKJYWQXHG-RDNQFMDVSA-N
SMILES :C[C@]12[C@@]([C@@](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)(C)CCC1)(CCC(=C)[C@H]2CCC=4C(=O)OCC4)[H]
Synonymes :- (5S,6S,10R)-17-(beta-D-glucopyranosyloxy)-20-oxo-9,19-didehydro-5,6,7,8,9,10,11,12,15-decahydro-20:5,10-dicycloretinal
- 2(5H)-Furanone, 3-[2-[(1R,4aS,5R,8aS)-5-[(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-
- 2(5H)-Furanone, 3-[2-[5-[(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-, [1R-(1α,4aβ,5α,8aα)]-
- 3-[2-[(1R,4aS,5R,8aS)-5-[(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone
- 3-[2-[(4aS,5R,8aS)-5,8a-Dimethyl-2-methylidene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-5H-furan-2-one
- 5β,9β<span class="text-smallcaps">H</span>,10α-Labda-8(20),13-dien-16-oic acid, 18-(glucosyloxy)-15-hydroxy-, γ-lactone
- Neoandrographiside
- {(1R,4aS,8aS)-1,4a-dimethyl-6-methylidene-5-[2-(2-oxo-2,5-dihydrofuran-3-yl)ethyl]decahydronaphthalen-1-yl}methyl beta-D-glucopyranoside
- 2(5H)-Furanone, 3-[2-[5-[(β-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-, [1R-(1α,4aβ,5α,8aα)]-
- 5β,9βH,10α-Labda-8(20),13-dien-16-oic acid, 18-(glucosyloxy)-15-hydroxy-, γ-lactone
- 2(5H)-Furanone, 3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-
- 3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-Glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone
- Neoandrographolide
- Neoandrographolide (Neoandrographiside)
- 3-(2-((1S,4aS,5R,8aS)-5,8a-Dimethyl-2-methylene-5-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)methyl)-decahydronaphthalen-1-yl)ethyl)furan-2(5H)-one
- Andrographolide Impurity 7
- 19-hydroxy-8(17),13-laboiadien-16,15-olide-o-βD-glucopyranoside
- ANDROGRAPHOLIDE, NEO(P)
- 3-[2-[(1R,4aβ)-5α-[(β-D-Glucopyranosyloxy)methyl]decahydro-5,8aα-dimethyl-2-methylenenaphthalen-1α-yl]ethyl]furan-2(5H)-one
- 3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-Glucopyranosyloxy)methyl]-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,8a-dimethyl-2-methylenenaphthalene-1-yl]ethyl]-2(5H)-furanone
- D-Glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone
- ANDROGRAPHOLIDE, NEO-
- ent-19-Hydroxy-8(17),13-labdadien-16,15-olide 19-O-β-D-glucopyranoside
- ANDROGRAPHOLIDE, NEO(SH)
- Neoandrographolide USP/EP/BP
- 4-[2-[(4aS,5R,8aS)-5,8a-dimethyl-2-methylidene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-2H-furan-5-one
- Voir plus de synonymes
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10 produits concernés.
Neoandrographolide
CAS :Formule :C26H40O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.5910Neoandrographolide
CAS :Formule :C26H40O8Degré de pureté :≥ 98.0%Couleur et forme :White to off-white powderMasse moléculaire :480.59Neoandrographolide
CAS :Neoandrographolide has antiradical, anti-inflammatory,and hypolipidemic effects, it protects the cardiovascular without significant liver damage. Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP)-overexpressing Jurkat cells, a model for chemoresistance.Neoandrographolide inhibits iNOS and COX-2 expression through inhibiting p38 MAPKs activation.Formule :C26H40O8Degré de pureté :95%~99%Masse moléculaire :480.598Neoandrographolide
CAS :Formule :C26H40O8Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :480.60Neoandrographolide
CAS :Neoandrographolide has hypolipidemic, cardio-protective, anti-inflammatory effects, and enhances chemo-sensitivity without major liver harm.Formule :C26H40O8Degré de pureté :98.52% - 99.00%Couleur et forme :Less Columnar Crystal Colorless Columnar CrystalMasse moléculaire :480.59Neoandrographolide
CAS :Natural glycosideFormule :C26H40O8Degré de pureté :≥ 95.0 % (HPLC)Couleur et forme :PowderMasse moléculaire :480.6Neoandrographolide
CAS :Produit contrôlé<p>Applications Neoandrographolide is one of the principle diterpenoids isolated from A. paniculata, a well-recognized medicinal plant in Asia.<br>References Jarukamjorn, K., et al.: J. Health Sci., 54, 370-381 (2008);<br></p>Formule :C26H40O8Couleur et forme :NeatMasse moléculaire :480.59Neoandrographolide
CAS :<p>Neoandrographolide is a diterpene compound that has been shown to have a significant cytotoxic effect on HL-60 cells. It also shows matrix effects in body formation and chemiluminescence. Neoandrographolide is extracted from the plant Andrographis paniculata, which belongs to the family Acanthaceae. This plant has been used historically as a medical herb in China and India for centuries. The extract of this plant has shown anti-inflammatory properties and can be used to treat infectious diseases such as bowel disease.</p>Formule :C26H40O8Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :480.6 g/mol3-(2-((1R,4aS,5R,8aS)-5,8a-Dimethyl-2-methylene-5-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)decahydronaphthalen-1-yl)ethyl)furan-2(5H)-one
CAS :Degré de pureté :98%Masse moléculaire :480.5979919
