CAS 2801785-12-4

FAK-IN-26

CAS : 2801785-12-4

FAK-IN-26 is a blood-brain barrier-penetrating inhibitor of Focal Adhesion Kinase (FAK) with an IC50 of 0.87 nM. It significantly reduces tumor cell viability, cancer stem cell activity, and cell migration in A549 and SKOV-3 cell lines. FAK-IN-26 exhibits potent anticancer activity, achieving tumor inhibition rates of 59.15% and 57.9% in A549 and SKOV-3 tumor mouse models, respectively.

Formule : C₂₀H₁₉BrFN₅O₂

Couleur et forme : Solid

Masse moléculaire : 460.30

Ref: TM-T207475