CAS 283172-68-9

WD2000-012547

CAS : 283172-68-9

WD2000-012547 is a potent and selective activator of the GPRC6A receptor, which is implicated in the regulation of pain sensitivity. WD2000-012547 was shown to be a high affinity ligand for the GPRC6A receptor, with a Ki value of 1.5 nM. It also inhibited protein phosphatase 2A at micromolar concentrations, which may account for its analgesic effects. WD2000-012547 has been shown to have no effect on ion channels or on cell viability and proliferation in vitro. This compound has not been tested in vivo but can be used as a research tool for studying the role of GPRC6A receptors in pain sensitivity.

Formule : C₁₇H₁₄N₂O

Degré de pureté : Min. 95%

Masse moléculaire : 262.3 g/mol

Ref: 3D-ILA17268

WD2000-012547

CAS : 283172-68-9

WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).

Formule : C₁₇H₁₄N₂O

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 262.31

Ref: TM-T13333