CAS 2841750-32-9

6-Chloro-1,5-dihydro-7-(4-methylphenyl)imidazo[2,1-b]quinazolin-2(3H)-one

Formule : C₁₇H₁₄ClN₃O

Synonymes :

• 6-Chloro-1,5-dihydro-7-(4-methylphenyl)imidazo[2,1-b]quinazolin-2(3H)-one
• Antitumor agent-100

Antitumor agent-100

CAS : 2841750-32-9

Antitumor Agent-100 (compound A6) is a molecular gel and apoptosis inducer targeting PDE3A-SLFN12 with an IC50 of 0.3 μM, demonstrating potent antitumor activity. This orally available agent binds to the PDE3A enzyme pocket, recruiting and stabilizing SLFN12 which disrupts protein translation and induces apoptosis [1].

Formule : C₁₇H₁₄ClN₃O

Couleur et forme : Solid

Masse moléculaire : 311.77

Ref: TM-T85701