CAS 2897640-93-4

PROTAC HER2 degrader-1

CAS : 2897640-93-4

PROTACHER2 degrader-1 is a highly selective HER2 PROTAC degrader with a DC50 of 69 nM and a Dmax of 96%. It effectively inhibits HER2-positive cell proliferation and tumor growth by inducing sustained HER2 degradation and strongly inhibiting downstream pathways (AKT and ERK). Additionally, PROTACHER2 degrader-1 can induce apoptosis in BT-474 cells and is useful for researching HER2-positive cancers.

Formule : C₄₉H₅₅N₁₁O₇

Couleur et forme : Solid

Masse moléculaire : 910.03

Ref: TM-T211553