CAS 3053755-09-9

LMP7/LMP2-IN-1

CAS : 3053755-09-9

LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.

Formule : C₁₆H₂₇BN₄O₃

Couleur et forme : Soild

Masse moléculaire : 334.22

Ref: TM-T88971