CAS 3058330-82-5

PD-M6

CAS : 3058330-82-5

PD-M6 is an mTOR PROTAC degrader with a DC50 of 4.8 μM, which facilitates the ubiquitination and degradation of mTOR. It inhibits the proliferation of cancer cell lines HeLa, MCF-7, and HepG2 with IC50 values of 11.3, 2.58, and 3.23 μM, respectively, and induces autophagy. Additionally, PD-M6 specifically targets the degradation of the key protein LAMTOR1 in the mTOR signaling pathway.

Formule : C₃₀H₃₉N₉O₆

Couleur et forme : Solid

Masse moléculaire : 621.69

Ref: TM-T207406