CAS 3062175-62-3

FAK-IN-24

CAS : 3062175-62-3

FAK-IN-24 (Compound 9f) is a potent FAK inhibitor with an IC50 of 0.815 nM. It induces DNA damage and apoptosis, and exhibits activity against glioblastoma. FAK-IN-24 effectively inhibits proliferation of glioblastoma cell lines U87-MG (IC50= 15 nM) and U251 (IC50= 20 nM), and suppresses tumor growth in U87-MG xenograft models.

Formule : C₃₉H₄₅Cl₂F₃N₈O₃

Couleur et forme : Solid

Masse moléculaire : 801.728

Ref: TM-T205467