CAS 3066143-73-2

HDAC1-IN-8

CAS : 3066143-73-2

HDAC1-IN-8 (compound 5c) is a potent and selective HDAC1 inhibitor, with IC50 values of 11.94 µM for HDAC1, 22.95 µM for HDAC6, and greater than 500 µM for HDAC8. It exhibits antiproliferative activity, induces cell cycle arrest in G1 and G2/M phases, and triggers autophagy (autophagy). Additionally, HDAC1-IN-8 demonstrates anticancer properties and holds potential for lung cancer research.

Formule : C₂₂H₂₄N₂O₄

Couleur et forme : Solid

Masse moléculaire : 380.437

Ref: TM-T204224