CAS 3081246-18-3

CDK9/EZH2-IN-1

CAS : 3081246-18-3

CDK9/EZH2-IN-1 is a dual-target inhibitor of CDK9 and EZH2 with IC50 values of 83.9 nM and 108.6 nM, respectively. It induces apoptosis and causes DNA double-strand breaks (DSB). Additionally, CDK9/EZH2-IN-1 inhibits the proliferation of MKN45, MDA-MB-453, and SW620 cancer cells, with respective IC50 values of 136.3 nM, 171.3 nM, and 315.7 nM.

Formule : C₄₇H₅₉N₁₁O₄S₂

Couleur et forme : Solid

Masse moléculaire : 906.17

Ref: TM-T207528