CAS 3081687-67-1

P2Y14R antagonist 4

CAS : 3081687-67-1

Compound 25l, also known as P2Y14R antagonist 4, is an orally active antagonist of the P2Y14R receptor with an IC50 of 5.6 nM. It exhibits higher binding affinity for P2Y14R compared to other PPTN receptors. P2Y14R antagonist 4 also possesses anti-inflammatory properties, reducing the release of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α) induced by LPS.

Formule : C₂₇H₂₇F₃N₂O₄S

Couleur et forme : Solid

Masse moléculaire : 532.574

Ref: TM-T206785