CAS 333415-38-6

VU0071063

CAS : 333415-38-6

VU0071063

Degré de pureté : ≥98%

Masse moléculaire : 326.39g/mol

Ref: 54-BUP10552

VU0071063

CAS : 333415-38-6

VU0071063 is a Kir6.2/SUR1 activator.

Formule : C₁₈H₂₂N₄O₂

Degré de pureté : 99.33%

Couleur et forme : Solid

Masse moléculaire : 326.39

Ref: TM-T26324

7-(4-(tert-Butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

CAS : 333415-38-6

Degré de pureté : 98%

Masse moléculaire : 326.3999939

Ref: 10-F867478

VU0071063

Produit contrôlé

CAS : 333415-38-6

VU0071063 is a small molecule that inhibits the mitochondrial membrane potential, which prevents hyperinsulinism. It has been shown to have a pharmacokinetic property that makes it suitable for oral administration. VU0071063 is metabolized in the liver, but penetrates the blood-brain barrier and reaches high concentrations in the pancreas. The compound has a low toxicity profile and shows no appreciable cardiotoxicity. VU0071063 inhibits both subunits of ATP synthase, preventing movement of potassium ions across the mitochondrial membrane and increasing intracellular calcium ion levels. This leads to impaired insulin secretion by pancreatic β-cells, as well as decreased ATP production by other cells.

Formule : C₁₈H₂₂N₄O₂

Degré de pureté : Min. 95%

Masse moléculaire : 326.39 g/mol

Ref: 3D-INA41538