CAS 353484-30-7

2-Bromo-3b,6,6a,7,9,9a,10,12a-octahydrobenzo[ij]dicyclopenta[b,g]quinolizine-7-carboxylic acid

CAS : 353484-30-7

2-Bromo-3b,6,6a,7,9,9a,10,12a-octahydrobenzo[ij]dicyclopenta[b,g]quinolizine-7-carboxylic acid (BQCA) is a potent and selective inhibitor of the ion channels TRPV1 and TRPA1. BQCA is an antagonist of the N-methyl-D-aspartate receptor (NMDAR), GABA A receptor (GABA A R), alpha 1A adrenergic receptor (alpha 1A AR), alpha 2A adrenergic receptor (alpha 2A AR), alpha 2C adrenergic receptor (alpha 2C AR), beta 3 adrenergic receptor (beta 3 AR) and 5HT2C receptors. It also inhibits peptide ligands for these receptors. While BQCA is a potent inhibitor of ion channels in vitro at high concentrations (>50 μM), it does

Formule : C₁₉H₁₈BrNO₂

Degré de pureté : Min. 95%

Masse moléculaire : 372.3 g/mol

Ref: 3D-DPA48430

LDN-0088050

CAS : 353484-30-7

LDN 0088050 inhibits FABP4 (Ki=0.29 μM) and FABP3 (Ki=1.3 μM) with FABP4 binding affinity (Kd=2.05 μM).

Formule : C₁₉H₁₈BrNO₂

Couleur et forme : Solid

Masse moléculaire : 372.26

Ref: TM-T37614