CAS 356068-97-8

N-Desethylsunitinib

CAS : 356068-97-8

Couleur et forme : Neat

Ref: 61-FOR3568.06

Desethyl Sunitinib ((Z)-N-(2-(ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide)

CAS : 356068-97-8

Lactams, nesoi

Formule : C₂₀H₂₃FN₄O₂

Couleur et forme : Orange Solid

Masse moléculaire : 370.1805

Ref: 45-1A05060

N-Desethyl Sunitinib

CAS : 356068-97-8

Formule : C₂₀H₂₃FN₄O₂

Degré de pureté : 97%

Masse moléculaire : 370.4206

Ref: IN-DA007A8Y

N-Desethyl Sunitinib

CAS : 356068-97-8

Formule : C₂₀H₂₃FN₄O₂

Couleur et forme : Orange Solid

Masse moléculaire : 370.43

Ref: 4Z-S-412

N-Desethylsunitinib

Produit contrôlé

CAS : 356068-97-8

Formule : C₂₀H₂₃FN₄O₂

Couleur et forme : Neat

Masse moléculaire : 370.42

Ref: 86-MM3568.06

N-Desethyl Sunitinib

CAS : 356068-97-8

N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,

Formule : C₂₀H₂₃FN₄O₂

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 370.42

Ref: TM-T12145

N-Desethyl sunitinib

CAS : 356068-97-8

N-Desethyl sunitinib is an active metabolite of sunitinib. It has been shown to have antitumor response in experimental models, suggesting that it may be a potential biomarker for renal cell cancer. Sunitinib is used in the treatment of cancers such as renal cell cancer and gastrointestinal stromal tumor. N-Desethyl sunitinib has also been shown to affect drug metabolism through the induction of CYP3A4 and CYP2D6, which can lead to drug interactions. This metabolite is detected in human serum by high performance liquid chromatography with a matrix effect analyzer, but not by LC-MS/MS.

Formule : C₂₀H₂₃FN₄O₂

Degré de pureté : Min. 95 Area-%

Couleur et forme : Powder

Masse moléculaire : 370.42 g/mol

Ref: 3D-FD21182

N-Desethyl Sunitinib-d4 Maleate

Produit contrôlé

CAS : 356068-97-8

Applications N-Desethyl Sunitinib-d4 Maleate, is the labeled analogue of N-Desethyl Sunitinib (D289650), a metabolite of Sunitinib (S820000).
References Sun, L., et al.: J. Med. Chem., 46, 1116 (2003), Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003), Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004), Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004),

Formule : C₂₀H₁₉D₄FN₄O₂•C₄H₄O₄

Couleur et forme : Neat

Masse moléculaire : 347.4511607

Ref: TR-D289653

N-Desethyl Sunitinib

CAS : 356068-97-8

Formule : C₂₀H₂₃FN₄O₂

Masse moléculaire : 370.43

Ref: ST-EA-CP-S42022