CAS 356068-99-0

Sunitinib N-Oxide ((Z)-N,N-diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethan-1-amine oxide)

CAS : 356068-99-0

Lactams, nesoi

Formule : C₂₂H₂₇FN₄O₃

Couleur et forme : Yellow Orange Solid

Masse moléculaire : 414.20672

Ref: 45-1A05050

Sunitinib N-Oxide

CAS : 356068-99-0

Formule : C₂₂H₂₇FN₄O₃

Couleur et forme : Orange Solid

Masse moléculaire : 414.48

Ref: 4Z-S-415

Sunitinib N-Oxide

CAS : 356068-99-0

Couleur et forme : Neat

Ref: 86-MM3568.05

Sunitinib N-Oxide

CAS : 356068-99-0

Formule : C₂₂H₂₇FN₄O₃

Masse moléculaire : 414.48

Ref: ST-EA-CP-S42009

Sunitinib N-Oxide

CAS : 356068-99-0

Stability Hygroscopic
Applications Sunitinib N-Oxide, is a derivative of Sunitinib (S820000), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK), used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor. It is a COVID19-related research product.
References Sun, L., et al.: J. Med. Chem., 46, 1116 (2003), Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003), Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004), Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004),

Formule : C₂₂H₂₇FN₄O₃

Couleur et forme : Neat

Masse moléculaire : 414.47

Ref: TR-S820005

Sunitinib N-Oxide-d10

Produit contrôlé

CAS : 356068-99-0

Formule : C₂₂D₁₀H₁₇FN₄O₃

Couleur et forme : Neat

Masse moléculaire : 424.535

Ref: TR-S820007

Sunitinib N-oxide

CAS : 356068-99-0

Sunitinib N-oxide is the active form of sunitinib, a drug that is used to treat cancer. Sunitinib N-oxide is a photolabile n-oxide and can be converted to sunitinib by exposure to light. This conversion process can be used as an analytical technique for determining the concentration of the drug in blood or tissue samples. Sunitinib N-oxide has been shown to reduce tumor growth in mouse models and also inhibits angiogenesis and tumor metastasis. The drug has also been shown to have anti-inflammatory effects, which may be due to its inhibition of prostaglandin synthesis.

Formule : C₂₂H₂₇FN₄O₃

Degré de pureté : Min. 95%

Couleur et forme : White Powder

Masse moléculaire : 414.47 g/mol

Ref: 3D-FS146111