CAS 372198-97-5

Org 24598

CAS : 372198-97-5

A selective inhibitor of glial glycine transporter type 1 (GlyT-1b). It has no considerable affinity for noradrenaline, dopamine, serotonin and GABA receptors. Increases amplitude of electronically evoked NMDA receptor-mediated glutamatergic excitatory postsynaptic current (eEPSCs). This raises glycine levels in spinal cord slides and extends the duration of current at glycinergic synapses.

Formule : C₁₉H₂₀F₃NO₃

Degré de pureté : Min. 95%

Masse moléculaire : 367.36 g/mol

Ref: 3D-FO100627

Org 24598

CAS : 372198-97-5

Potent GlyT1b inhibitor, IC50 = 6.9 nM; little effect on GlyT-2, adrenoceptors, dopamine, 5HT receptors, GABA transporters.

Formule : C₁₉H₂₀F₃NO₃

Couleur et forme : Solid

Masse moléculaire : 367.36

Ref: TM-T37699

Org 24598

CAS : 372198-97-5

Formule : C₁₉H₂₀F₃NO₃

Degré de pureté : 98%

Masse moléculaire : 367.3622

Ref: IN-DA00CHVH