CAS 38363-42-7

(R)-Penbutolol Sulfate

Produit contrôlé

CAS : 38363-42-7

Applications (R)-Penbutolol Sulfate is an isomer of Penbutolol (P220500); a β-adrenoceptor antagonist and antihypertensive.
References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994); Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003)

Formule : C₃₆H₅₈N₂O₄(H₂SO₄)

Couleur et forme : Neat

Masse moléculaire : 582.86

Ref: TR-P220510

(R)-Penbutolol sulfate

CAS : 38363-42-7

(R)-Penbutolol sulfate is a racemic mixture of the two enantiomers of penbutolol. Racemic penbutolol sulfate is an optical isomer of propranolol, which belongs to the group of beta-adrenergic receptor antagonists. It has a matrix effect, which means that it can be used in tablet form and will not dissolve in the stomach acid. Racemic penbutolol sulfate blocks pro-inflammatory signaling by inhibiting the activity of pcsk9 (proprotein convertase subtilisin/kexin type 9), which prevents cholesterol from being converted into bile acids. This drug has been shown to lower blood pressure in humans and is used to treat hypertension and heart failure. Racemic penbutolol sulfate has been shown to have an inhibitory effect on influenza virus replication through inhibition of viral dna replication, as well as enhancement on anti-pcsk9 antibody activity. In clinical trials

Formule : C₃₆H₅₈N₂O₄(H₂SO₄)

Degré de pureté : Min. 95%

Masse moléculaire : 582.86 g/mol

Ref: 3D-NBA36342