CAS 3892-78-2

Fluphenazine-N-2-chloroethane (hydrochloride)

CAS : 3892-78-2

Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.

Formule : C₂₂H₂₇Cl₃F₃N₃S

Couleur et forme : Solid

Masse moléculaire : 528.89

Ref: TM-T36820

10-{3-[4-(2-Chloro-ethyl)-piperazin-1-yl]-propyl}-2-trifluoromethyl-10H-phenothiazine

CAS : 3892-78-2

10-{3-[4-(2-Chloro-ethyl)-piperazin-1-yl]-propyl}-2-trifluoromethyl-10H-phenothiazine is a nonselective, competitive antagonist of glutamate and quinpirole. It has been shown to block the glutamate receptors in the brain and reduce dopamine release. 10-[3-[4-(2-Chloro-ethyl)-piperazin-1-yl]-propyl]-2-trifluoromethylphenothiazine has a high affinity for the ryanodine receptor, which is found in the sarcoplasmic reticulum of striatal neurons. This drug also binds to calmodulin with high affinity, which may account for its ability to inhibit covalent adducts of dopamine to proteins. 10-[3-[4-(2-Chloro-ethyl)-piperazin-1-yl

Formule : C₂₂H₂₆Cl₂F₃N₃S

Degré de pureté : Min. 95%

Masse moléculaire : 492.4 g/mol

Ref: 3D-DAA89278